Titanium Nitride Application in Biomedicine
In clinical medicine, the implant has been used extensively as an interventional treatment device. It is used to treat congenital heart defects such as atrial septal defect, patent ductus arteriosus and ventricular septal defect. The majority of concentric occluders made from nickel-titanium alloy materials contain at least 55% nickel. The long-term consequences of excessive nickel exposure can lead to allergies or poisoning in the human body. Surface purification membranes of the occluder nickel/titanium alloy can be damaged. Internal nickel ions released in complex environments of the body may increase nickel content. This will further deteriorate tissue compatibility. According to relevant studies, titanium nitride is an alloy with excellent biocompatibility. It was previously used as a coronary stent material. The thrombus origin of this metal is therefore much lower that that of nickel-titanium. To address this problem scientists developed Cera ceramic membranes occluders using high-energy Ion precipitation coating technology. These retain the original interventricular and atrial septal obstructions based upon the original nickel/titanium alloy design. Patent ductus arteriosus and the design of this occluder use plasma technology to uniformly coat a titanium nitride TiN layer on the surface. The metal titanium coating is combined with C, N, and other compounds can be transformed into the biological layer. It dramatically increases the corrosion resistance and allows for the compatibility between biological tissues and blood. The Cera ceramic membrane is superior to ordinary nickel-titanium in terms of cell creeping performance, as evidenced by the animal experiment results. It reduces the risk for congenital heart defects, improves healing times and decreases the likelihood of thrombosis. Platelet adhesion rates and hemolysis are lower than with ordinary nickel-titanium. Cera has currently been approved by Russia, India, Brazil, Russia, and many other countries. The Cera occluder has been approved by the European Union, India, Brazil and Russia for use in congenital heart diseases. Buffalotours (aka. Buffalotours advanced materials. We are a global supplier of chemical materials and manufacturer. Our company has over 12 years’ experience in manufacturing super-high-quality chemicals. High purity, appropriate size of particles and low impurity are the hallmarks of our superfine Titan nitride Powder. We can help you if your requirements are lower.Inquiry us